A Targeted RNAi Screen of the Breast Cancer Genome Identifies KIF14 and TLN1 as Genes That Modulate Docetaxel Chemosensitivity in Triple-Negative Breast Cancer

PURPOSE: To identify biomarkers within the breast cancer genome that may predict chemosensitivity in breast cancer. EXPERIMENTAL DESIGN: We conducted an RNA interference (RNAi) screen within the breast cancer genome for genes whose loss-of-function enhanced docetaxel chemosensitivity in an estrogen...

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Publié dans:Clin Cancer Res
Auteurs principaux: Singel, Stina Mui, Cornelius, Crystal, Batten, Kimberly, Fasciani, Gail, Wright, Woodring E., Lum, Lawrence, Shay, Jerry W.
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513911/
https://ncbi.nlm.nih.gov/pubmed/23479679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0082
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