Identification of the minimal cytolytic unit for streptolysin S and an expansion of the toxin family

BACKGROUND: Streptolysin S (SLS) is a cytolytic virulence factor produced by the human pathogen Streptococcus pyogenes and other Streptococcus species. Related “SLS-like” toxins have been characterized in select strains of Clostridium and Listeria, with homologous clusters bioinformatically identifi...

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Veröffentlicht in:BMC Microbiol
Hauptverfasser: Molloy, Evelyn M., Casjens, Sherwood R., Cox, Courtney L., Maxson, Tucker, Ethridge, Nicole A., Margos, Gabriele, Fingerle, Volker, Mitchell, Douglas A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513790/
https://ncbi.nlm.nih.gov/pubmed/26204951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-015-0464-y
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