Nicotine attenuates the effect of HIV-1 proteins on the neural circuits of working and contextual memories

BACKGROUND: Human immunodeficiency virus (HIV)-1-associated neurocognitive disorders (HAND) are characterized by synaptic damage and neuronal loss in the brain. Excessive glutamatergic transmission and loss of cholinergic neurons are the major indicators of HAND. Nicotine acts as a cholinergic chann...

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Bibliografiske detaljer
Udgivet i:Mol Brain
Main Authors: Nesil, Tanseli, Cao, Junran, Yang, Zhongli, Chang, Sulie L., Li, Ming D.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513611/
https://ncbi.nlm.nih.gov/pubmed/26205781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0134-x
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