Role of Wnt/β-catenin and RANKL/OPG in bone healing of diabetic Charcot arthropathy patients: A prospective study in 24 patients followed for 2 years

BACKGROUND AND PURPOSE: Charcot neuropathy is characterized by bone destruction in a foot leading to deformity, instability, and risk of amputation. Little is known about the pathogenic mechanisms. We hypothesized that the bone-regulating Wnt/β-catenin and RANKL/OPG pathways have a role in Charcot a...

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Bibliografiske detaljer
Udgivet i:Acta Orthop
Main Authors: Folestad, Agnetha, Ålund, Martin, Asteberg, Susanne, Fowelin, Jesper, Aurell, Ylva, Göthlin, Jan, Cassuto, Jean
Format: Artigo
Sprog:Inglês
Udgivet: Informa Healthcare 2015
Fag:
Ankle, Foot
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513595/
https://ncbi.nlm.nih.gov/pubmed/25811776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/17453674.2015.1033606
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