Implementation of genome-wide complex trait analysis to quantify the heritability in multiple myeloma

A sizeable fraction of multiple myeloma (MM) is expected to be explained by heritable factors. Genome-wide association studies (GWAS) have successfully identified a number of common single-nucleotide polymorphisms (SNPs) influencing MM risk. While these SNPs only explain a small proportion of the ge...

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Publicado no:Sci Rep
Main Authors: Mitchell, Jonathan S., Johnson, David C., Litchfield, Kevin, Broderick, Peter, Weinhold, Niels, Davies, Faith E., Gregory, Walter A., Jackson, Graham H., Kaiser, Martin, Morgan, Gareth J., Houlston, Richard S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513545/
https://ncbi.nlm.nih.gov/pubmed/26208354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12473
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