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Post-transcriptional regulation of BRCA1 through its coding sequence by the miR-15/107 group of miRNAs

MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression that act by degrading their RNA targets or by repressing the translation of messenger RNAs (mRNAs). Initially thought to primarily target the 3′ untranslated region (3′UTR) of mRNAs, miRNAs have since been shown to a...

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Detalles Bibliográficos
Publicado en:Front Genet
Main Authors: Quann, Kevin, Jing, Yi, Rigoutsos, Isidore
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513244/
https://ncbi.nlm.nih.gov/pubmed/26257769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00242
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