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CRISPR-Cas9-Mediated Genome Editing in Leishmania donovani

The prokaryotic CRISPR (clustered regularly interspaced short palindromic repeat)-Cas9, an RNA-guided endonuclease, has been shown to mediate efficient genome editing in a wide variety of organisms. In the present study, the CRISPR-Cas9 system has been adapted to Leishmania donovani, a protozoan par...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Zhang, Wen-Wei, Matlashewski, Greg
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513079/
https://ncbi.nlm.nih.gov/pubmed/26199327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00861-15
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