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‘Chronomics’ in ICU: circadian aspects of immune response and therapeutic perspectives in the critically ill

Complex interrelations exist between the master central clock, located in the suprachiasmatic nuclei of the hypothalamus, and several peripheral clocks, such as those found in different immune cells of the body. Moreover, external factors that are called ‘timekeepers’, such as light/dark and sleep/w...

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Detalhes bibliográficos
Publicado no:Intensive Care Med Exp
Main Authors: Papaioannou, Vasilios, Mebazaa, Alexandre, Plaud, Benoît, Legrand, Matthieu
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513032/
https://ncbi.nlm.nih.gov/pubmed/26266918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2197-425X-2-18
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