Angiotensin-(1-7) improves oxygenation, while reducing cellular infiltrate and fibrosis in experimental Acute Respiratory Distress Syndrome

BACKGROUND: The renin-angiotensin system (RAS) plays a role in the pathogenesis of ARDS, Angiotensin II (Ang-II) contributing to the pathogenesis of inflammation and fibrogenesis. Angiotensin-(1-7) (Ang-(1-7)) may antagonize the effects of Ang-II. This study was aimed at evaluating the potential for...

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Bibliografiske detaljer
Udgivet i:Intensive Care Med Exp
Main Authors: Zambelli, Vanessa, Bellani, Giacomo, Borsa, Roberto, Pozzi, Federico, Grassi, Alice, Scanziani, Margherita, Castiglioni, Vittoria, Masson, Serge, Decio, Alessandra, Laffey, John G, Latini, Roberto, Pesenti, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512981/
https://ncbi.nlm.nih.gov/pubmed/26215809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-015-0044-3
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