Effect of long-term proton pump inhibitor therapy and healing effect of irsogladine on nonsteroidal anti-inflammatory drug-induced small-intestinal lesions in healthy volunteers

This study assessed time-course changes of the small intestinal lesions during long-term treatment with diclofenac sodium plus omeprazole and the effects of irsogladine on such lesions. Thirty two healthy volunteers were treated with diclofenac sodium (75 mg/day) plus omeprazole (10 mg/day) for 6 we...

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Bibliographic Details
Published in:J Clin Biochem Nutr
Main Authors: Kojima, Yuichi, Takeuchi, Toshihisa, Ota, Kazuhiro, Harada, Satoshi, Edogawa, Shoko, Narabayashi, Ken, Nouda, Sadaharu, Okada, Toshihiko, Kakimoto, Kazuki, Kuramoto, Takanori, Inoue, Takuya, Higuchi, Kazuhide
Format: Artigo
Language:Inglês
Published: the Society for Free Radical Research Japan 2015
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512901/
https://ncbi.nlm.nih.gov/pubmed/26236102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.15-32
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