De novo mutations from sporadic schizophrenia cases highlight important signaling genes in an independent sample

Schizophrenia is a debilitating syndrome with high heritability. Genomic studies reveal more than a hundred genetic variants, largely nonspecific and of small effect size, and not accounting for its high heritability. De novo mutations are one mechanism whereby disease related alleles may be introdu...

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Detalhes bibliográficos
Publicado no:Schizophr Res
Main Authors: Kranz, Thorsten M, Harroch, Sheila, Manor, Orly, Lichtenberg, Pesach, Friedlander, Yechiel, Seandel, Marco, Harkavy-Friedman, Jill, Walsh-Messinger, Julie, Dolgalev, Igor, Heguy, Adriana, Chao, Moses V, Malaspina, Dolores
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512856/
https://ncbi.nlm.nih.gov/pubmed/26091878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2015.05.042
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