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OTX2 Transcription Factor Controls Regional Patterning Within The Medial Ganglionic Eminence (MGE) And Regional Identity Of The Septum

The Otx2 homeodomain transcription factor is essential for gastrulation and early neural development. We generated Otx2 conditional knockout (cKO) mice to investigate its roles in telencephalon development after neurulation (~E9.0). We conducted transcriptional profiling and in situ hybridization to...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Hoch, Renée V., Lindtner, Susan, Price, James D., Rubenstein, John L.R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512845/
https://ncbi.nlm.nih.gov/pubmed/26166575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.06.043
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