Inducible nitric oxide synthase gene methylation and parkinsonism in manganese-exposed welders

INTRODUCTION: Neurologist-assessed parkinsonism signs are prevalent among workers exposed to manganese (Mn)-containing welding fume. Neuroinflammation may possibly play a role. Inducible nitric oxide synthase, coded by NOS2, is involved in inflammation, and particulate exposure increases the gene’s...

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Pubblicato in:Parkinsonism Relat Disord
Autori principali: Nielsen, Susan Searles, Checkoway, Harvey, Criswell, Susan R., Farin, Federico M., Stapleton, Patricia L., Sheppard, Lianne, Racette, Brad A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512640/
https://ncbi.nlm.nih.gov/pubmed/25634431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2015.01.007
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