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Evaluation of Ancestral Sequence Reconstruction Methods to Infer Nonstationary Patterns of Nucleotide Substitution

Inference of gene sequences in ancestral species has been widely used to test hypotheses concerning the process of molecular sequence evolution. However, the approach may produce spurious results, mainly because using the single best reconstruction while ignoring the suboptimal ones creates systemat...

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Pubblicato in:Genetics
Autori principali: Matsumoto, Tomotaka, Akashi, Hiroshi, Yang, Ziheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512549/
https://ncbi.nlm.nih.gov/pubmed/25948563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.177386
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