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Chronic ethanol exposure combined with high fat diet up-regulates P2X7 receptors that parallels neuroinflammation and neuronal loss in C57BL/6J mice

The present investigation tested the role of ATP-activated P2X7 receptors (P2X7Rs) in alcohol-induced brain damage using a model that combines intragastric (iG) ethanol feeding and high fat diet in C57BL/6J mice (Hybrid). The Hybrid paradigm caused increased levels of pro-inflammatory markers, chang...

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Detalhes bibliográficos
Publicado no:J Neuroimmunol
Main Authors: Asatryan, Liana, Khoja, Sheraz, Rodgers, Kathleen E, Alkana, Ronald L, Tsukamoto, Hidekatsu, Davies, Daryl L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512299/
https://ncbi.nlm.nih.gov/pubmed/26198936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2015.06.007
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