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Quantitative and functional interrogation of parent-of-origin allelic expression biases in the brain

The maternal and paternal genomes play different roles in mammalian brains as a result of genomic imprinting, an epigenetic regulation leading to differential expression of the parental alleles of some genes. Here we investigate genomic imprinting in the cerebellum using a newly developed Bayesian s...

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Publicat a:eLife
Autors principals: Perez, Julio D, Rubinstein, Nimrod D, Fernandez, Daniel E, Santoro, Stephen W, Needleman, Leigh A, Ho-Shing, Olivia, Choi, John J, Zirlinger, Mariela, Chen, Shau-Kwaun, Liu, Jun S, Dulac, Catherine
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512258/
https://ncbi.nlm.nih.gov/pubmed/26140685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07860
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