Gene-Environment Interactions of Circadian-Related Genes for Cardiometabolic Traits

OBJECTIVE: Common circadian-related gene variants associate with increased risk for metabolic alterations including type 2 diabetes. However, little is known about whether diet and sleep could modify associations between circadian-related variants (CLOCK-rs1801260, CRY2-rs11605924, MTNR1B-rs1387153,...

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Pubblicato in:Diabetes Care
Autori principali: Dashti, Hassan S., Follis, Jack L., Smith, Caren E., Tanaka, Toshiko, Garaulet, Marta, Gottlieb, Daniel J., Hruby, Adela, Jacques, Paul F., Kiefte-de Jong, Jessica C., Lamon-Fava, Stefania, Scheer, Frank A.J.L., Bartz, Traci M., Kovanen, Leena, Wojczynski, Mary K., Frazier-Wood, Alexis C., Ahluwalia, Tarunveer S., Perälä, Mia-Maria, Jonsson, Anna, Muka, Taulant, Kalafati, Ioanna P., Mikkilä, Vera, Ordovás, José M., Lemaitre, Rozenn N., Partonen, Timo, Ebeling, Tapani, Hopkins, Paul N., Paternoster, Lavinia, Lahti, Jari, Hernandez, Dena G., Toft, Ulla, Saxena, Richa, Vitezova, Anna, Kanoni, Stavroula, Raitakari, Olli T., Psaty, Bruce M., Perola, Markus, Männistö, Satu, Straka, Robert J., Hansen, Torben, Räikkönen, Katri, Ferrucci, Luigi, Grarup, Niels, Johnson, W. Craig, Rallidis, Loukianos, Kähönen, Mika, Siscovick, David S., Havulinna, Aki S., Astrup, Arne, Jørgensen, Torben, Chen, Tzu-An, Hofman, Albert, Deloukas, Panos, Viikari, Jorma S.A., Mozaffarian, Dariush, Pedersen, Oluf, Rotter, Jerome I., Uitterlinden, André G., Seppälä, Ilkka, Tiemeier, Henning, Salomaa, Veikko, Gharib, Sina A., Borecki, Ingrid B., Arnett, Donna K., Sørensen, Thorklid I.A., Eriksson, Johan G., Bandinelli, Stefania, Linneberg, Allan, Rich, Stephen S., Franco, Oscar H., Dedoussis, George, Lehtimäki, Terho
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2015
Soggetti:
Epidemiology/Health Services Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512139/
https://ncbi.nlm.nih.gov/pubmed/26084345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc14-2709
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