Functional role of miR-10b in tamoxifen resistance of ER-positive breast cancer cells through down-regulation of HDAC4

BACKGROUND: For breast cancer patients diagnosed with estrogen receptor (ER)-positive tumors, treatment with tamoxifen is the gold standard. A significant number of patients, however, develop resistance to tamoxifen, and management of such tamoxifen-resistant patients is a major clinical challenge....

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Ahmad, Aamir, Ginnebaugh, Kevin R., Yin, Shuping, Bollig-Fischer, Aliccia, Reddy, Kaladhar B., Sarkar, Fazlul H.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512090/
https://ncbi.nlm.nih.gov/pubmed/26206152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1561-x
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