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Lactose-Functionalized Dendrimers Arbitrate the Interaction of Galectin-3/MUC1 Mediated Cancer Cellular Aggregation

By using lactose-functionalized poly(amidoamine) dendrimers as a tunable multivalent platform, we studied cancer cell aggregation in three different cell lines (A549, DU-145, and HT-1080) with galectin-3. We found that small lactose-functionalized G(2)-dendrimer 1 inhibited galectin-3-induced aggreg...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Michel, Anna K., Nangia-Makker, Pratima, Raz, Avraham, Cloninger, Mary J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511962/
https://ncbi.nlm.nih.gov/pubmed/25138772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402134
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