Virulence of Group A Streptococci Is Enhanced by Human Complement Inhibitors

Streptococcus pyogenes, also known as Group A Streptococcus (GAS), is an important human bacterial pathogen that can cause invasive infections. Once it colonizes its exclusively human host, GAS needs to surmount numerous innate immune defense mechanisms, including opsonization by complement and cons...

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Udgivet i:PLoS Pathog
Main Authors: Ermert, David, Shaughnessy, Jutamas, Joeris, Thorsten, Kaplan, Jakub, Pang, Catherine J., Kurt-Jones, Evelyn A., Rice, Peter A., Ram, Sanjay, Blom, Anna M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511809/
https://ncbi.nlm.nih.gov/pubmed/26200783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005043
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