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Spontaneous Cell Competition in Immortalized Mammalian Cell Lines

Cell competition is a form of cell-cell interaction by which cells compare relative levels of fitness, resulting in the active elimination of less-fit cells, “losers,” by more-fit cells, “winners.” Here, we show that in three routinely-used mammalian cell lines – U2OS, 3T3, and MDCK cells – sub-clon...

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Veröffentlicht in:PLoS One
Hauptverfasser: Penzo-Méndez, Alfredo I., Chen, Yi-Ju, Li, Jinyang, Witze, Eric S., Stanger, Ben Z.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511643/
https://ncbi.nlm.nih.gov/pubmed/26200654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132437
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