Predictive and Prognostic Value of Ribonucleotide Reductase Regulatory Subunit M1 and Excision Repair Cross-Complementation Group 1 in Advanced Urothelial Carcinoma (UC) Treated with First-Line Gemcitabine Plus Platinum Combination Chemotherapy

Preclinical and clinical studies have suggested that expression of ribonucleotide reductase regulatory subunit M1 (RRM1) and excision repair cross-complementation group 1 (ERCC1) is associated with resistance to gemcitabine and cisplatin, respectively. We evaluated the significance of RRM1 and ERCC1...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Miso, Ku, Ja Hyeon, Kwak, Cheol, Kim, Hyeon Hoe, Lee, Eunsik, Keam, Bhumsuk, Kim, Tae Min, Heo, Dae Seog, Lee, Se-Hoon, Moon, Kyung Chul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511592/
https://ncbi.nlm.nih.gov/pubmed/26200905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133371
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