Role of membrane Hsp70 in radiation sensitivity of tumor cells

BACKGROUND: The major stress-inducible heat shock protein 70 (Hsp70) is frequently overexpressed in the cytosol and integrated in the plasma membrane of tumor cells via lipid anchorage. Following stress such as non-lethal irradiation Hsp70 synthesis is up-regulated. Intracellular located Hsp70 is kn...

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Detalhes bibliográficos
Publicado no:Radiat Oncol
Main Authors: Murakami, Naoya, Kühnel, Annett, Schmid, Thomas E., Ilicic, Katarina, Stangl, Stefan, Braun, Isabella S., Gehrmann, Mathias, Molls, Michael, Itami, Jun, Multhoff, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511458/
https://ncbi.nlm.nih.gov/pubmed/26197988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-015-0461-1
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