Enhanced epithelial to mesenchymal transition (EMT) and upregulated MYC in ectopic lesions contribute independently to endometriosis

BACKGROUND: Epithelial to mesenchymal transition (EMT) is a process in which epithelial cells lose polarity and cell-to-cell contacts and acquire the migratory and invasive abilities of mesenchymal cells. These abilities are thought to be prerequisites for the establishment of endometriotic lesions....

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Detalhes bibliográficos
Publicado no:Reprod Biol Endocrinol
Main Authors: Proestling, Katharina, Birner, Peter, Gamperl, Susanne, Nirtl, Nadine, Marton, Erika, Yerlikaya, Gülen, Wenzl, Rene, Streubel, Berthold, Husslein, Heinrich
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511248/
https://ncbi.nlm.nih.gov/pubmed/26198055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-015-0063-7
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