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A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration
Although cell migration plays a central role in development and disease, the underlying molecular mechanism is not fully understood. Here we report that a phosphorylation-mediated molecular switch comprising deleted in liver cancer 1 (DLC1), tensin-3 (TNS3), phosphatase and tensin homologue (PTEN) a...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Pub. Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4510974/ https://ncbi.nlm.nih.gov/pubmed/26166433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8721 |
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