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Targeted Detection of G-Quadruplexes in Cellular RNAs**

The G-quadruplex (G4) is a non-canonical nucleic acid structure which regulates important cellular processes. RNA G4s have recently been shown to exist in human cells and be biologically significant. Described herein is a new approach to detect and map RNA G4s in cellular transcripts. This method ex...

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Publicat a:Angew Chem Int Ed Engl
Autors principals: Kwok, Chun Kit, Balasubramanian, Shankar
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510783/
https://ncbi.nlm.nih.gov/pubmed/25907625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201500891
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