9-O-Acetylation of sialic acids is catalysed by CASD1 via a covalent acetyl-enzyme intermediate

Sialic acids, terminal sugars of glycoproteins and glycolipids, play important roles in development, cellular recognition processes and host–pathogen interactions. A common modification of sialic acids is 9-O-acetylation, which has been implicated in sialoglycan recognition, ganglioside biology, and...

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Pubblicato in:Nat Commun
Autori principali: Baumann, Anna-Maria T., Bakkers, Mark J. G., Buettner, Falk F. R., Hartmann, Maike, Grove, Melanie, Langereis, Martijn A., de Groot, Raoul J., Mühlenhoff, Martina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510713/
https://ncbi.nlm.nih.gov/pubmed/26169044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8673
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