K-bZIP Mediated SUMO-2/3 Specific Modification on the KSHV Genome Negatively Regulates Lytic Gene Expression and Viral Reactivation

SUMOylation is associated with epigenetic regulation of chromatin structure and transcription. Epigenetic modifications of herpesviral genomes accompany the transcriptional switch of latent and lytic genes during the virus life cycle. Here, we report a genome-wide comparison of SUMO paralog modifica...

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Vydáno v:PLoS Pathog
Hlavní autoři: Yang, Wan-Shan, Hsu, Hung-Wei, Campbell, Mel, Cheng, Chia-Yang, Chang, Pei-Ching
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510548/
https://ncbi.nlm.nih.gov/pubmed/26197391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005051
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