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The Association of LINE-1 Hypomethylation with Age and Centromere Positive Micronuclei in Human Lymphocytes

Global hypomethylation in white blood cell (WBC) DNA has recently been proposed as a potential biomarker for determining cancer risk through genomic instability. However, the amplitude of the changes associated with age and the impacts of environmental factors on DNA methylation are unclear. In this...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cho, Yoon Hee, Woo, Hae Dong, Jang, Yoonhee, Porter, Virginia, Christensen, Sonja, Hamilton, Raymond F., Chung, Hai Won
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510364/
https://ncbi.nlm.nih.gov/pubmed/26196382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133909
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