Correlation of sensitizing capacity and T-cell recognition within the Bet v 1 family

BACKGROUND: Bet v 1 is the main sensitizing allergen in birch pollen. Like many other major allergens, it contains an immunodominant T cell–activating region (Bet v 1(142-156)). Api g 1, the Bet v 1 homolog in celery, lacks the ability to sensitize and is devoid of major T-cell epitopes. OBJECTIVE:...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Kitzmüller, Claudia, Zulehner, Nora, Roulias, Anargyros, Briza, Peter, Ferreira, Fatima, Faé, Ingrid, Fischer, Gottfried F., Bohle, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Mosby 2015
Assuntos:
Mechanisms of Allergy and Clinical Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510200/
https://ncbi.nlm.nih.gov/pubmed/25670010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.12.1928
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