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Gene Replacement for the Generation of Designed Novel Avermectin Derivatives with Enhanced Acaricidal and Nematicidal Activities

Avermectin (AVM) and ivermectin (IVM) are potent pesticides and acaricides which have been widely used during the past 30 years. As insect resistance to AVM and IVM is greatly increasing, alternatives are urgently needed. Here, we report two novel AVM derivatives, tenvermectin A (TVM A) and TVM B, w...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Huang, Jun, Chen, An-Liang, Zhang, Hui, Yu, Zhen, Li, Mei-Hong, Li, Na, Lin, Jia-Tan, Bai, Hua, Wang, Ji-Dong, Zheng, Yu-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510159/
https://ncbi.nlm.nih.gov/pubmed/26025902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01025-15
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