Hepatocyte Growth Factor Receptor c-Met Instructs T Cell Cardiotropism and Promotes T Cell Migration to the Heart via Autocrine Chemokine Release

Effector-T-cell-mediated immunity depends on the efficient localization of antigen-primed lymphocytes to antigen-rich non-lymphoid tissue, which is facilitated by the expression of a unique set of “homing” receptors acquired by memory T cells. We report that engagement of the hepatocyte growth facto...

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Udgivet i:Immunity
Main Authors: Komarowska, Izabela, Coe, David, Wang, Guosu, Haas, Robert, Mauro, Claudio, Kishore, Madhav, Cooper, Dianne, Nadkarni, Suchita, Fu, Hongmei, Steinbruchel, Daniel A., Pitzalis, Costantino, Anderson, Graham, Bucy, Pat, Lombardi, Giovanna, Breckenridge, Ross, Marelli-Berg, Federica M.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510150/
https://ncbi.nlm.nih.gov/pubmed/26070483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2015.05.014
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