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Efficacy of Simvastatin in Bone Regeneration After Surgical Removal of Mandibular Third Molars: A Clinical Pilot Study

INTRODUCTION: Simvastatin, a common cholesterol-lowering drug that inhibits hepatic hydroxymethylglutaryl coenzyme A reductase, the rate-limiting enzyme in the mevalonate pathway, increases expression of the BMP-2 gene and thus promotes bone regeneration. MATERIALS AND METHODS: A study was conducted...

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Bibliografske podrobnosti
izdano v:J Maxillofac Oral Surg
Main Authors: Chauhan, Anil Singh, Maria, Anisha, Managutti, Anil
Format: Artigo
Jezik:Inglês
Izdano: Springer India 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510091/
https://ncbi.nlm.nih.gov/pubmed/26225047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12663-014-0697-6
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