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Efficacy of Simvastatin in Bone Regeneration After Surgical Removal of Mandibular Third Molars: A Clinical Pilot Study
INTRODUCTION: Simvastatin, a common cholesterol-lowering drug that inhibits hepatic hydroxymethylglutaryl coenzyme A reductase, the rate-limiting enzyme in the mevalonate pathway, increases expression of the BMP-2 gene and thus promotes bone regeneration. MATERIALS AND METHODS: A study was conducted...
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| Publicado no: | J Maxillofac Oral Surg |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer India
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4510091/ https://ncbi.nlm.nih.gov/pubmed/26225047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12663-014-0697-6 |
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