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Gastric LTi cells promote lymphoid follicle formation but are limited by IRAK-M and do not alter microbial growth

Lymphoid tissue inducer (LTi) cells are activated by accessory cell IL-23, and promote lymphoid tissue genesis and antibacterial peptide production by the mucosal epithelium. We investigated the role of LTi cells in the gastric mucosa in the context of microbial infection. Mice deficient in IRAK-M,...

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Bibliographische Detailangaben
Veröffentlicht in:Mucosal Immunol
Hauptverfasser: Shiu, Jessica, Piazuelo, M. Blanca, Ding, Hua, Czinn, Steven J., Drakes, Maureen L., Banerjee, Aditi, Basappa, Nisha, Kobayashi, Koichi S., Fricke, W. Florian, Blanchard, Thomas G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510039/
https://ncbi.nlm.nih.gov/pubmed/25603827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2014.132
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