Natural Progression of Atherosclerosis from Pathologic Intimal Thickening to Late Fibroatheroma in Human Coronary Arteries: A Pathology Study

OBJECTIVE: Smooth muscle cells, macrophage infiltration and accumulation of lipids, proteoglycans, collagen matrix and calcification play a central role in atherosclerosis. The early histologic changes of plaque progression from pathologic intimal thickenings (PIT) to late fibroatheroma lesions have...

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Detalhes bibliográficos
Publicado no:Atherosclerosis
Main Authors: Otsuka, Fumiyuki, Kramer, Miranda C.A., Woudstra, Pier, Yahagi, Kazuyuki, Ladich, Elena, Finn, Aloke V., de Winter, Robbert J., Kolodgie, Frank D., Wight, Thomas N., Davis, Harry R., Joner, Michael, Virmani, Renu
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510015/
https://ncbi.nlm.nih.gov/pubmed/26058741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2015.05.011
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