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Genome-wide activities of Polycomb complexes control pervasive transcription

Polycomb group (PcG) complexes PRC1 and PRC2 are well known for silencing specific developmental genes. PRC2 is a methyltransferase targeting histone H3K27 and producing H3K27me3, essential for stable silencing. Less well known but quantitatively much more important is the genome-wide role of PRC2 t...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Lee, Hun-Goo, Kahn, Tatyana G., Simcox, Amanda, Schwartz, Yuri B., Pirrotta, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510001/
https://ncbi.nlm.nih.gov/pubmed/25986499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.188920.114
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