Mesenchymal Stem Cells Isolated from Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 pathway

Although mesenchymal stem cells (MSCs) have been implicated as stromal components of several cancers, their ultimate contribution to tumorigenesis and their potential to drive cancer stem cells, particularly in the unique microenvironment of human brain tumors, remains largely undefined. Consequentl...

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Udgivet i:Stem Cells
Main Authors: Hossain, Anwar, Gumin, Joy, Gao, Feng, Figueroa, Javier, Shinojima, Naoki, Takezaki, Tatsuya, Priebe, Waldemar, Villarreal, Diana, Kang, Seok-Gu, Joyce, Celine, Sulman, Erik, Wang, Qianghu, Marini, Frank C., Andreeff, Michael, Colman, Howard, Lang, Frederick F.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509942/
https://ncbi.nlm.nih.gov/pubmed/25966666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2053
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