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Mesenchymal Stem Cells Isolated from Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 pathway

Although mesenchymal stem cells (MSCs) have been implicated as stromal components of several cancers, their ultimate contribution to tumorigenesis and their potential to drive cancer stem cells, particularly in the unique microenvironment of human brain tumors, remains largely undefined. Consequentl...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Hossain, Anwar, Gumin, Joy, Gao, Feng, Figueroa, Javier, Shinojima, Naoki, Takezaki, Tatsuya, Priebe, Waldemar, Villarreal, Diana, Kang, Seok-Gu, Joyce, Celine, Sulman, Erik, Wang, Qianghu, Marini, Frank C., Andreeff, Michael, Colman, Howard, Lang, Frederick F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509942/
https://ncbi.nlm.nih.gov/pubmed/25966666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2053
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