PAT-seq: a method to study the integration of 3′-UTR dynamics with gene expression in the eukaryotic transcriptome

A major objective of systems biology is to quantitatively integrate multiple parameters from genome-wide measurements. To integrate gene expression with dynamics in poly(A) tail length and adenylation site, we developed a targeted next-generation sequencing approach, Poly(A)-Test RNA-sequencing. PAT...

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Vydáno v:RNA
Hlavní autoři: Harrison, Paul F., Powell, David R., Clancy, Jennifer L., Preiss, Thomas, Boag, Peter R., Traven, Ana, Seemann, Torsten, Beilharz, Traude H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2015
Témata:
Methods
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509939/
https://ncbi.nlm.nih.gov/pubmed/26092945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.048355.114
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