Inconsistency and features of single nucleotide variants detected in whole exome sequencing versus transcriptome sequencing: A case study in lung cancer

Whole exome sequencing (WES) and RNA sequencing (RNA-Seq) are two main platforms used for next-generation sequencing (NGS). While WES is primarily for DNA variant discovery and RNA-Seq is mainly for measurement of gene expression, both can be used for detection of genetic variants, especially single...

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Detalhes bibliográficos
Publicado no:Methods
Main Authors: O’Brien, Timothy D., Jia, Peilin, Xia, Junfeng, Saxena, Uma, Jin, Hailing, Vuong, Huy, Kim, Pora, Wang, Qingguo, Aryee, Martin J, Mino-Kenudson, Mari, Engelman, Jeffrey, Le, Long P., Iafrate, A. John, Heist, Rebecca S., Pao, William, Zhao, Zhongming
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509831/
https://ncbi.nlm.nih.gov/pubmed/25913717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2015.04.016
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