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Modulation of Cellular Insulin signaling and PTP1B effects by lipid metabolites in skeletal muscle cells

Normal glucose regulation is achieved by having adequate insulin secretion and effective glucose uptake/disposal. Excess lipids in peripheral tissues: skeletal muscle, liver and adipose tissue may attenuate insulin signaling through the protein kinase B (AKt/PKB) pathway and upregulate protein tyros...

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Bibliographic Details
Published in:J Nutr Biochem
Main Authors: Obanda, Diana N., Cefalu, William T.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509740/
https://ncbi.nlm.nih.gov/pubmed/23481236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2012.12.014
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