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Fluoro-sorafenib (Regorafenib) effects on hepatoma cells: growth inhibition, quiescence and recovery

To evaluate the growth-inhibitory properties of the potent multi-kinase antagonist Regorafenib (Fluoro-Sorafenib), which was synthesized as a more potent Sorafenib, a Raf inhibitor and to determine whether similar mechanisms were involved, human hepatoma cell lines were grown in the presence or abse...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: Carr, Brian I., Cavallini, Aldo, Lippolis, Catia, D’Alessandro, Rosalba, Messa, Caterina, Refolo, Maria Grazia, Tafaro, Angela
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509637/
https://ncbi.nlm.nih.gov/pubmed/22777740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24148
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