Decoupling of N-acetyl-aspartate and Glutamate Within the Dorsolateral Prefrontal Cortex in Schizophrenia

Aberrant function of glutamatergic pathways is likely to underlie the pathology of schizophrenia. Evidence of oxidative stress in the disease pathology has also been reported. N-Acetylaspartate (NAA) is metabolically linked to both cascades and may be a key marker in exploring the interconnection of...

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Pubblicato in:Curr Mol Med
Autori principali: Coughlin, Jennifer M., Tanaka, Teppei, Marsman, Anouk, Wang, Hongxing, Bonekamp, Susanne, Kim, Pearl K., Higgs, Cecilia, Varvaris, Mark, Edden, Richard A.E., Pomper, Martin, Schretlen, David, Barker, Peter B., Sawa, Akira
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509630/
https://ncbi.nlm.nih.gov/pubmed/25732147
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