Targeted multidrug-resistance reversal in tumor based on PEG-PLL-PLGA polymer nano drug delivery system

The study investigated the reversal of multidrug resistance (MDR) and the biodistribution of nanoparticles (NPs) that target leukemia cells in a nude mice model via a surface-bound transferrin (Tf). The cytotoxic cargo of daunorubicin (DNR) and tetrandrine (Tet) was protected in the NPs by an outer...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Guo, Liting, Zhang, Haijun, Wang, Fei, Liu, Ping, Wang, Yonglu, Xia, Guohua, Liu, Ran, Li, Xueming, Yin, Haixiang, Jiang, Hulin, Chen, Baoan
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509529/
https://ncbi.nlm.nih.gov/pubmed/26213467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S85587
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