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Simvastatin reverses cardiomyocyte hypertrophy via the upregulation of phosphatase and tensin homolog expression

The aim of the present study was to investigate the effects of simvastatin on the protein kinase B (PKB) signaling pathway and the expression of phosphatase and tensin homolog (PTEN). The effects of simvastatin were analyzed by administering the drug orally to male spontaneously hypertensive rats (S...

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Bibliografische gegevens
Gepubliceerd in:Exp Ther Med
Hoofdauteurs: CHEN, YONG-QING, ZHAO, LIAN-YOU, ZHANG, WEI-ZE, LI, TAO
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509020/
https://ncbi.nlm.nih.gov/pubmed/26622396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2015.2550
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