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Simvastatin reverses cardiomyocyte hypertrophy via the upregulation of phosphatase and tensin homolog expression

The aim of the present study was to investigate the effects of simvastatin on the protein kinase B (PKB) signaling pathway and the expression of phosphatase and tensin homolog (PTEN). The effects of simvastatin were analyzed by administering the drug orally to male spontaneously hypertensive rats (S...

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Publicat a:Exp Ther Med
Autors principals: CHEN, YONG-QING, ZHAO, LIAN-YOU, ZHANG, WEI-ZE, LI, TAO
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509020/
https://ncbi.nlm.nih.gov/pubmed/26622396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2015.2550
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