High frequency targetable EGFR mutations in sinonasal squamous cell carcinomas arising from inverted sinonasal papilloma

Inverted sinonasal papilloma (ISP) is a locally aggressive neoplasm associated with sinonasal squamous cell carcinoma (SNSCC) in 10-25% of cases. To date, no recurrent mutations have been identified in ISP or SNSCC. Using targeted next generation sequencing and Sanger sequencing, we identified activ...

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Publicat a:Cancer Res
Autors principals: Udager, Aaron M., Rolland, Delphine C.M., McHugh, Jonathan B., Betz, Bryan L., Murga-Zamalloa, Carlos, Carey, Thomas E., Marentette, Lawrence J., Hermsen, Mario A., DuRoss, Kathleen E., Lim, Megan S., Elenitoba-Johnson, Kojo S. J., Brown, Noah A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508878/
https://ncbi.nlm.nih.gov/pubmed/25931286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0340
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