Development and Validation of a GC-MS Method for the Detection and Quantification of Clotiapine in Blood and Urine Specimens and Application to a Postmortem Case

Introduction. Clotiapine is an atypical antipsychotic of the dibenzothiazepine class introduced in a few European countries since 1970, efficient in treatment-resistant schizophrenic patients. There is little published data on the therapeutic and toxic concentrations of this drug. Aims. The aim of t...

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Publicat a:Int J Anal Chem
Autors principals: Mannocchi, Giulio, Pantano, Flaminia, Tittarelli, Roberta, Catanese, Miriam, Umani Ronchi, Federica, Busardò, Francesco Paolo
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508480/
https://ncbi.nlm.nih.gov/pubmed/26236337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/972480
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