Comparison of Three Different FDA-Approved Plasma HIV-1 RNA Assay Platforms Confirms the Virologic Failure Endpoint of 200 Copies per Milliliter Despite Improved Assay Sensitivity

Discrepancies between HIV-1 RNA results assayed by different FDA-approved platforms have been reported. Plasma samples collected from 332 randomly selected clinical trial participants during the second year of antiretroviral treatment were assayed with three FDA-approved platforms: UltraSensitive Ro...

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Bibliographic Details
Published in:J Clin Microbiol
Main Authors: Lalama, Christina M., Jennings, Cheryl, Johnson, Victoria A., Coombs, Robert W., McKinnon, John E., Bremer, James W., Cobb, Bryan R., Cloherty, Gavin A., Mellors, John W., Ribaudo, Heather J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Virology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508432/
https://ncbi.nlm.nih.gov/pubmed/26063861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00801-15
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