Application of Quality by Design (QbD) Approach to Ultrasonic Atomization Spray Coating of Drug-Eluting Stents

The drug coating process for coated drug-eluting stents (DES) has been identified as a key source of inter- and intra-batch variability in drug elution rates. Quality-by-design (QbD) principles were applied to gain an understanding of the ultrasonic spray coating process of DES. Statistically based...

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Publicado en:AAPS PharmSciTech
Autores principales: McDermott, Martin, Chatterjee, Sharmista, Hu, Xiaoli, Ash-Shakoor, Ariel, Avery, Reginald, Belyaeva, Anastasiya, Cruz, Celia, Hughes, Minerva, Leadbetter, Joanne, Merkle, Conrad, Moot, Taylor, Parvinian, Sepideh, Patwardhan, Dinesh, Saylor, David, Tang, Nancy, Zhang, Tina
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508304/
https://ncbi.nlm.nih.gov/pubmed/25563817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0266-9
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