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The Effect of Streptozotocin and Alloxan on the mRNA Expression of Rat Hepatic Transporters In Vivo

The effect of streptozotocin (STZ) and alloxan (ALX) on the hepatic messenger RNA (mRNA) expression of four transporters (Mrp2, Mdr1, Oct1, and Oatp1) was studied in the present work. After the healthy male Wistar rats were individually treated by a single intraperitoneal injection of ALX monohydrat...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Zhai, Ting, Wang, Junjun, Sun, Lijuan, Chen, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4508290/
https://ncbi.nlm.nih.gov/pubmed/25549789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0262-0
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